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Year : 2017  |  Volume : 45  |  Issue : 2  |  Page : 68-72

Epidemiology of infection as a precipitating factor for diabetic ketoacidosis at Tanta University Hospital

1 Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt
2 Department of Public Health and Community Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

Correspondence Address:
Zeinab Shafeek Shafeek Hamed
Department of Internal Medicine, Faculty of Medicine Tanta University, Mitt Haway, Elsanta, Elgharbiya, 31746
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tmj.tmj_10_17

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Introduction Diabetic ketoacidosis (DKA) is one of the life-threatening sequels in diabetes mellitus. Nonadherence to treatment, infections, psychological troubles, and comorbid diseases were the main precipitating factors that trigger DKA. Aim Evaluate infection as a precipitating factor of DKA and its correction may contribute to improve outcome and decrease recurrence. Patients and methods This descriptive, cross-sectional study was conducted on 200 patients with DKA admitted to the Internal Medicine Department, Tanta University Hospital. All patients were subjected to history taking, clinical examination, routine investigations, glycosylated hemoglobin, and albumin–creatinine ratio. Results Our study included 86 men and 114 women. Of these, 113 patients were of type 2 diabetes, 83 patients were of type 1 diabetes, two patients were of secondary diabetes, and two patients were having gestational diabetes. Infection was the main precipitating factor of DKA (46.5%). The most common source of infections was urinary tract infections and respiratory tract infections (31.2, 26.8%, respectively). Infection was the precipitating cause in 38.5% of type 1 diabetes and 53.9% of type 2 diabetes with P value was 0.033. DKA was the first presentation of diabetes in 18.5% of patients. Stress, dietary errors, pregnancy, and nonidentified causes were 19%. Conclusion Infection is the main precipitating factor of DKA in patients of Tanta University Hospital.

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